Product Name | YAP Rabbit mAb |
Background | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013] |
Reactivity | Human; Mouse; Rat |
Source | Rabbit, IgG Kappa |
Applications | WB; IHC; IF; IP; ELISA |
Dilutions | WB: 1:500-1:2000; IHC: 1:100-1:500; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
Purification | Protein A |
Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
Storage and Stability | -20°C/1 year |
MW (kDa) | Calculated: 55; Observed: 55-75 |
UniProt Accession # | P46937 |
Protein Name | YAP |
Gene Name | YAP1 |
Gene ID | 10413 |
Other Names | YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65 |