| Product Name | TGF beta1/3 Rabbit mAb |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. |
| Reactivity | Human; Mouse; Rat |
| Source | Rabbit, IgG Kappa |
| Applications | WB; IF; IP; ELISA |
| Dilutions | WB: 1:500-1:2000; IHC: 1:1000-1:4000; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
| Purification | Protein A |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage and Stability | -20°C/1 year |
| MW (kDa) | Calculated: 44; Observed: 44,13 |
| UniProt Accession # | P01137; P10600; |
| Protein Name | TGF beta1/3 |
| Gene Name | TGFB1 TGFB3 |
| Gene ID | 7040;7043; |
| Other Names | Transforming growth factor beta-1 proprotein; Latency-associated peptide(LAP); Transforming growth factor beta-1(TGF-beta-1); Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3 (TGF-beta-3); |
