TFEB Rabbit Monoclonal Antibody

TFEB Rabbit Monoclonal Antibody

Clone ID: PT0684R

$230.00$600.00

Cat #: MR3493
Product NameSTAT5B Rabbit mAb
Background The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
ReactivityHuman, Mouse, Rat
SourceRabbit, IgG Kappa
ApplicationsWB; IHC; IF; IP; ELISA
DilutionsWB: 1:2000-1:10000; IHC: 1:1000-1:5000; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000
PurificationProtein A
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage and Stability-20°C/1 year
MW (kDa)Calculated: 90; Observed: 90
UniProt Accession #P51692
Protein NameSTAT5B
Gene NameSTAT5B
Gene ID6777
Other NamesSignal transducer and activator of transcription 5B