Product Name | RIP3 Rabbit mAb |
Background | The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008] |
Reactivity | Mouse |
Source | Rabbit, IgG Kappa |
Applications | WB; IF; IP; ELISA |
Dilutions | WB: 1:2000-1:10000; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
Purification | Protein A |
Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
Storage and Stability | -20°C/1 year |
MW (kDa) | Calculated: 50; Observed: 50 |
UniProt Accession # | Q9Y572 |
Protein Name | RIP3 |
Gene Name | RIPK3 RIP3 |
Gene ID | 11035 |
Other Names |