| Product Name | Rab 5A Rabbit mAb |
| Background | Enzyme Regulation: Regulated by guanine nucleotide exchange factors (GEFs), which promote the exchange of bound GDP for free GTP. Function: Required for the fusion of plasma membranes and early endosomes. Similarity: Belongs to the small GTPase superfamily, Rab family. Subcellular Location: Enriched in stage I melanosomes. Subunit: Binds to EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, likely by acting as GEFs. Also interacts with ALS2CL, UNC84B, ZFYVE20, and RUFY1. Additionally, it interacts with SGSM1 and SGSM3. |
| Reactivity | Human; Mouse; Rat |
| Source | Rabbit, IgG Kappa |
| Applications | WB; IHC; IF; IP; ELISA |
| Dilutions | WB: 1:1000-1:5000; IHC: 1:1000-1:4000; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
| Purification | Protein A |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage and Stability | -20°C/1 year |
| MW (kDa) | Calculated: 24; Observed: 24 |
| UniProt Accession # | P20339 |
| Protein Name | Rab 5A |
| Gene Name | RAB5A |
| Gene ID | 5868 |
| Other Names | RAB5A; RAB5; Ras-related protein Rab-5A |