| Product Name | Parkin Rabbit mAb |
| Background | The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008] |
| Reactivity | Human, Mouse, Rat |
| Source | Rabbit, IgG Kappa |
| Applications | WB; IF; IP; ELISA |
| Dilutions | WB: 1:2000-1:10000; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
| Purification | Protein A |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage and Stability | -20°C/1 year |
| MW (kDa) | Calculated: 52; Observed: 52 |
| UniProt Accession # | O60260 |
| Protein Name | Parkin |
| Gene Name | PARK2 |
| Gene ID | 5071 |
| Other Names | PARK2; PRKN; E3 ubiquitin-protein ligase parkin; Parkinson juvenile disease protein 2; Parkinson disease protein 2 |
