Product Name | p21 Rabbit mAb |
Background | his gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
Reactivity | Human; Rat |
Source | Rabbit, IgG Kappa |
Applications | WB; IHC; IF; IP; ELISA |
Dilutions | WB: 1:1000-1:5000; IHC: 1:100-1:200; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
Purification | Protein A |
Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
Storage and Stability | -20°C/1 year |
MW (kDa) | Calculated: 18; Observed: 18 |
UniProt Accession # | P38936 |
Protein Name | p21 |
Gene Name | CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 |
Gene ID | 1026 |
Other Names | Cyclin-dependent kinase inhibitor 1 ; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21; |