HDAC4 Rabbit Monoclonal Antibody

HDAC4 Rabbit Monoclonal Antibody

Clone ID: PT0600R

$230.00$600.00

Cat #: MR3409
Product NameHDAC4 Rabbit mAb
Background Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
ReactivityHuman; Mouse; Rat
SourceRabbit, IgG Kappa
ApplicationsWB; IHC; IF; IP; ELISA
DilutionsWB: 1:2000-1:10000; IHC: 1:50-1:200; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000
PurificationProtein A
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage and Stability-20°C/1 year
MW (kDa)Calculated: 119; Observed: 140
UniProt Accession #P56524
Protein NameHDAC4
Gene NameHDAC4
Gene ID9759
Other NamesHDAC4; KIAA0288; Histone deacetylase 4; HD4