Glutamine Synthetase Rabbit Monoclonal Antibody

Glutamine Synthetase Rabbit Monoclonal Antibody

Clone ID: PT0057R

 

$230.00$600.00

Cat #: MR3029

Datasheet

Product NameGlutamine Synthetase Rabbit mAb
Background The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
ReactivityHuman; Mouse; Rat
SourceRabbit, IgG Kappa
ApplicationsWB; IHC; IF; IP; ELISA
DilutionsWB: 1:1000-1:5000; IHC: 1:1000-1:4000; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000
PurificationProtein A
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage and Stability-20°C/1 year
UniProt Accession #P15104
Protein NameGlutamine Synthetase
Gene Name>>Arginine biosynthesis;>>Alanine, aspartate and glutamate metabolism;>>Glyoxylate and dicarboxylate metabolism;>>Nitrogen metabolism;>>Metabolic pathways;>>Biosynthesis of amino acids;>>Necroptosis;>>Glutamatergic synapse;>>GABAergic synapse
Gene ID2752
Other NamesGLUL; GLNS; Glutamine synthetase; GS; Glutamate decarboxylase;Glutamate--ammonia ligase