| Product Name | FXR1 Rabbit mAb |
| Background | FXR1 is an RNA-binding protein involved in RNA transport, stability, and translation regulation. It is closely related to FMR1 and FXR2 and plays a crucial role in muscle development, synaptic function, and sleep regulation. FXR1 is highly expressed in muscle tissue, where it assembles target mRNAs into cytoplasmic ribonucleoprotein granules, supporting muscle growth and maintenance. Mutations in FXR1 are linked to congenital multi-minicore myopathy, a severe muscle disorder. Additionally, FXR1 is implicated in neurodevelopmental and psychiatric disorders, as well as in various cancers, where it influences tumor growth and metastasis. |
| Reactivity | Human; Mouse; Rat |
| Source | Rabbit, IgG Kappa |
| Applications | WB; IHC; IF; IP; ELISA |
| Dilutions | WB: 1:1000-1:5000; IHC: 1:200-1:1000; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
| MW (kDa) | Calculated: 70; Observed: 70-84 |
| Purification | Protein A |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage and Stability | -20°C/1 year |
| UniProt Accession # | P51114 |
| Protein Name | FXR1 |
| Gene Name | FXR1 |
| Gene ID | 8087 |
| Other Names | Fragile X mental retardation syndrome-related protein 1 (hFXR1p) |