| Product Name | COX2 Rabbit mAb |
| Background | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009] |
| Reactivity | Human; Mouse; Rat |
| Source | Rabbit, IgG Kappa |
| Applications | WB; IHC; IF; ELISA |
| Dilutions | WB: 1:1000-1:5000; IHC: 1:100-1:500; IF: 1:200-1:1000; ELISA: 1:5000-1:20000 |
| Purification | Protein A |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage and Stability | -20°C/1 year |
| MW (kDa) | Calculated: 69; Observed: 75 |
| UniProt Accession # | P35354 |
| Protein Name | COX2 |
| Gene Name | PTGS2 COX2 |
| Gene ID | 5743 |
| Other Names | Cyclooxygenase-2, PHS II Prostaglandin H2 synthase 2 (PGH synthase 2; PGHS-2) Prostaglandin-endoperoxide synthase 2 |