BACE Rabbit Monoclonal Antibody

BACE Rabbit Monoclonal Antibody

Clone ID: PT0655R

$230.00$600.00

Cat #: MR3464
Product NameBACE Rabbit mAb
Background This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]
ReactivityHuman, Mouse, Rat
SourceRabbit, IgG Kappa
ApplicationsWB; IHC; IF; IP; ELISA
DilutionsWB: 1:1000-1:5000; IHC: 1:100-1:400; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000
PurificationProtein A
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage and Stability-20°C/1 year
MW (kDa)Calculated: 56; Observed: 70
UniProt Accession #P56817
Protein NameBACE
Gene NameBACE1
Gene ID23621
Other NamesBACE1; BACE; KIAA1149; Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2