ATP-Citrate Lyase Rabbit Monoclonal Antibody

ATP-Citrate Lyase Rabbit Monoclonal Antibody

Clone ID: PT0552R

 

$230.00$600.00

Cat #: MR3372
Product NameATP-Citrate Lyase Rabbit mAb
Background ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
ReactivityHuman; Mouse; Rat
SourceRabbit, IgG Kappa
ApplicationsWB; IHC; IF; IP; ELISA
DilutionsWB: 1:2000-1:10000; IHC: 1:2000-1:10000; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000
PurificationProtein A
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage and Stability-20°C/1 year
MW (kDa)Calculated: 121; Observed: 121
UniProt Accession #P53396
Protein NameATP-Citrate Lyase
Gene NameACLY
Gene ID47
Other NamesACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme