Product Name | ATG7 Rabbit mAb |
Background | This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Reactivity | Human; Mouse; Rat |
Source | Rabbit, IgG Kappa |
Applications | WB; IHC; IF; IP; ELISA |
Dilutions | WB: 1:1000-1:5000; IHC: 1:200-1:1000; IF: 1:200-1:1000; IP: 1:50-1:200; ELISA: 1:5000-1:20000 |
Purification | Protein A |
Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
Storage and Stability | -20°C/1 year |
MW (kDa) | Calculated: 78; Observed: 78 |
UniProt Accession # | O95352 |
Protein Name | ATG7 |
Gene Name | ATG7 APG7L |
Gene ID | 10533 |
Other Names | Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7; APG7-like; hAGP7; Ubiquitin-activating enzyme E1-like protein) |